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KMID : 0857220050090020387
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Journal of the Korean Pediatric Cardiology Society
2005 Volume.9 No. 2 p.387 ~ p.393
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A Case of Typical Kawasaki Disease with Vulvar Erythema and Edema in 21 Days Old Neonate
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Yun Sin-Weon
Yoo Byung-Hoon
Lee Kang-Won
Chae Soo-Ahn
Lim In-Seok
Lee Dong-Keun
Choi Eung-Sang
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Abstract
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Kawasaki diseases occur frequently in children beyond the age of 4 years, but classic Kawasaki disease in newborns are rare and have not been reported in Korea yet. We report a case of classic Kawasaki disease in neonate who is 21 days old girl and has no response to gamma-globulin although early diagnosis and treatment. Her clinical features met typical Kawasaki disease, but unusually she had a non suppurative labia major erythema and severe edema instead of cervical lymphadenitis. She had persistent fever and progressive carditis with coronary dilatation in spite of 3 doses of gamma globulin. Her fever was subsided after 3 doses of intravenous methyl prednisolone. In the subacute stage her other symptoms subsided and appeared typical desquamation of fingers and toe. Finally she had mild mitral regurgitation and diffuse coronary dilatation when she was discharged. Since one year follow up, with continuous aspirin medication, now she is very healthy, and her coronary dilatation was normalized and not any more valvular regurgitation.
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KEYWORD
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Kawasaki disease, Neonate, Vulvar erythema, Coronary dilatation
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